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Bacterial cellulose membranes as drug delivery systems: An in vivo skin compati...
Almeida, IF; Pereira, T; Silva, NH; Gomes, FP; Silvestre, AJ; Freire, CS; Sousa-Lobo, JM; Costa, PCBacterial cellulose (BC) is a highly pure form of cellulose, produced in the form of a swollen membrane by several bacteria that demonstrated to be able to modulate the skin release of model drugs. In the present study, the skin irritation potential of BC was evaluated in human subjects. BC membranes with and without glycerin (acting as plasticizer) were tested. No significant differences were observed for tran...
In vivo Skin Irritation Potential of a Castanea sativa (Chestnut) Leaf Extract,...
Almeida, IF; Valentão, P; Andrade, PB; Seabra, RM; Pereira, TM; Amaral, MH; Costa, PC; Bahia, MFTopical application of natural antioxidants has proven to be effective in protecting the skin against ultraviolet-mediated oxidative damage and provides a straightforward way to strengthen the endogenous protection system. However, natural products can provoke skin adverse effects, such as allergic and irritant contact dermatitis. Skin irritation potential of Castanea sativa leaf ethanol:water (7:3) extract was...
In vivo Skin Irritation Potential of a Castanea sativa (Chestnut) Leaf Extract,...
Almeida, IF; Valentão, P; Andrade, PB; Seabra, RM; Pereira, TM; Amaral, MH; Costa, PC; Bahia, MFTopical application of natural antioxidants has proven to be effective in protecting the skin against ultraviolet-mediated oxidative damage and provides a straightforward way to strengthen the endogenous protection system. However, natural products can provoke skin adverse effects, such as allergic and irritant contact dermatitis. Skin irritation potential of Castanea sativa leaf ethanol:water (7:3) extract was...
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