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Performance of gentamicin population kinetic parameters in Portuguese neonates
Rocha, Marília J.; Almeida, Anabela M.; Falcão, Amílcar C.; Caramona, Margarida M.Aim: To evaluate the performance of eight different sets of gentamicin populational pharmacokinetic parameters, regarding potential implementation in clinical pharmacokinetic software as prior information. Methods: The study involved 49 patients of 31.3±4.1 weeks of gestational age (GA), receiving gentamicin, and for whom peak and trough concentrations were obtained. Accuracy and precision were assessed by mean...
Performance of gentamicin population kinetic parameters in Portuguese neonates
Rocha, Marília J.; Almeida, Anabela M.; Falcão, Amílcar; Caramona, Margarida M.Aim: To evaluate the performance of eight different sets of gentamicin populational pharmacokinetic parameters, regarding potential implementation in clinical pharmacokinetic software as prior information. Methods: The study involved 49 patients of 31.3±4.1 weeks of gestational age (GA), receiving gentamicin, and for whom peak and trough concentrations were obtained. Accuracy and precision were assessed by mean...
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