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First in vivo MRI assessment of a self-assembled metallostar compound endowed w...
Livramento, J. B.; Weidensteiner, C.; Prata, M. I. M.; Allegrini, P. R.; Geraldes, C. F. G. C.; Helm, L.; Kneuer, R.; Merbach, A. E.; Santos, A. C.Fe[Gd2bpy(DTTA)2(H2O)4]34- is a self-assembled, metallostar-structured potential MRI contrast agent, with six efficiently relaxing Gd3+ centres confined into a small molecular space. Its proton relaxivity is particularly remarkable at very high magnetic fields (r1 = 15.8 mM-1 s-1 at 200 MHz, 37°C, in H2O). Here we report the first in vivo MRI feasibility study, complemented with dynamic gamma scintigraphic imag...
Data: 2006
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Origem: Estudo Geral - Universidade de Coimbra
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