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Síndrome de Churg-Strauss: casuística

Alfaro, TM; Duarte, C; Monteiro, R; Simão, A; Calretas, S; Nascimento-Costa, JM

Churg-Strauss syndrome (CSS) is a systemic necrotizing vasculitis of the small and medium vessels, associated with extravascular eosinophilic granulomas, peripheral eosinophilia and asthma. This is a rare syndrome of unknown etiology, affecting both genders and all age groups. CSS patients usually respond well to steroid treatment, although relapses are common after it ends. Timely diagnosis and treatment gener...


Doença associada ao Clostridium difficile – aumento dramático da incidência em ...

Correia, L; Monteiro, R; Alfaro, TM; Simão, A; Carvalho, A; Nascimento-Costa, JM

Many publications show an incidence increase of Clostridium difficile (CD) associated disease (CDAD), affecting both in- and outpatients being these recent infections more severe and difficult to treat. The aim of this retrospective study is to evaluate the incidence and clinical impact of CDAD in patients hospitalized from the 1st January 2004 to the 31st December 2009. Suggestive clinical manifestations and a...


Organizing pneumonia due to actinomycosis: an undescribed association

Alfaro, TM; Bernardo, J; Garcia, H; Alves, F; Carvalho, L; Caseiro-Alves, F; Robalo-Cordeiro, C

Organizing pneumonia is a pathologic entity characterized by intra-alveolar buds of granulation tissue that can extend to the bronchiolar lumen. It is a non-specific finding reflecting a pattern of pulmonary response to aggression that can be cryptogenic or associated with several causes. Pulmonary actinomycosis is a rare infectious disease, of bacterial aetiology, and of difficult diagnosis. This disease usual...


Bronchoalveolar lavage in occupational lung diseases

Robalo-Cordeiro, C; Cemlyn-Jones, J; Alfaro, TM; Ferreira, AJ

Occupational lung diseases (OLDs) are related to the exposure and inhalation of organic, inorganic, and synthetic particles, fumes, gases, or infectious agents. From the long list of OLDs this article focuses the discussion on bronchoalveolar lavage (BAL) in parenchymal immunoinflammatory conditions, such as hypersensitivity pneumonitis (HP) and pneumoconiosis. Several antigens may cause HP, including products ...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia