It has been described alterations of the thyroid function in patients with chronic renal disease without primary disease of the thyroid gland. Nevertheless primary hypothyroidism is more frequent in this population than in other non renal chronic disease. Authors report two cases of hypothyroidism diagnosed in infants with terminal renal failure in the neonatal period, secondary to renal hypoplasia / dysplasia,...
The electronic effects induced by p-substituents on the phenyl ring of several novel cross-conjugated carbonyl compounds [4-p-R-phenyl-1-(1,3-dithiolane-2-ylidene)-3 E-butene-2-one, where R= NO2, Cl, Br, OMe, NEt2 (2-6),] and their reactivity towards Fe2(CO)9 have been studied using a Hammett plot. The structure of two compounds (3 and 4b) was fully established by X-ray diffraction analysis.
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