Encontrados 2 documentos, a visualizar página 1 de 1
Synthesis and kinetic investigation of the selective acydolysis of para-substit...
Lima, Sílvia M. M. A. Pereira; Pinto, Filipa C. S. C.; Ventura, Cristina; Albuquerque, Lídia; Maia, Raquel M. Gonçalves; Maia, Hernâni L. S.Several derivatives of N-phenylacetyl-N-benzyl-alpha,alpha-dimethylglycine cyclohexylamide and their alpha,alpha-dibenzylglycine analogues were synthesised by a Ugi-Passerini reaction. In addition, a few analogues of the former but having an N-phenyl instead of a benzyl group at the nitrogen atom were synthesised. The compounds in each of these three sets differed from each other at the position 4 of the N-benz...
Kinetic investigation of the effect of the amino acid side chains in the select...
Wei-Qun, Jiang; Lima, Sílvia M. M. A. Pereira; Ventura, Cristina; Costa, Susana P. G.; Albuquerque, Lídia; Maia, Raquel M. GonçalvesAccurate kinetic measurements of the rate constants for the acidolysis of five N-acetyl-N-(4-methoxybenzyl)-alfa,alfa-trialkyl glycine cyclohexyl amides in TFA were performed at 25.00 ºC and the reactions monitored by HPLC. The results were in all cases consistent with a first order behaviour with respect to the substrate. No direct correlation was obtained with this data between rate constant values and struct...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||