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Synthesis of 2-{2-[5(4)-aryl-2H-[1,2,3]-triazol-4(5)-yl]vinyl}chromen-4-ones

Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José A.S.

Chromones are a family of oxygen-containing heterocyclic compounds that have been shown particular relevant biological activity. In what concerns to 2-methylchromones, their reactivity is well-known and allowed to exploit many different kinds of chemical reactions. The acidic character of the 2-methyl group, due to the low electron density at C-2 caused by carbonyl group enable this class of compounds to underg...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Synthesis of (E)-2-(4-Arylbut-1-en-3-ynyl)-4H-chromen-4-ones

Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José A.S.

Chromones are a well-known class of naturally occurring oxygen-containing heterocyclic compounds; many of them playing important biological functions in nature.[IJ Although 2- methylchromones are one of the scarcest classes of natural chromones, their synthesis and reactivity is well studied. They can participate in several chemical transformations such as oxidation, thiation, hydrogenation, photolysis, cycload...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Synthesis of (E)-2-(4-Arylbut-1-en-3-ynyl)-4H-chromen-4-ones

Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José A.S.

Chromones are a well-known class of naturally occurring oxygencontaining heterocyclic compounds; many of them playing important biological functions in nature [1]. Although 2-methylchromones are one of the scarcest classes of natural chromones, their synthesis and reactivity is well studied. They can participate in several chemical transformations such as oxidation, thiation, hydrogenation, photolysis, cycloadd...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Synthesis of 2-{2-[5(4)-aryl-2H-[1,2,3]-triazol-4(5)-yl]vinyl}chromen-4-ones

Albuquerque, Hélio; Santos, Clementina M.M.; Silva, Artur; Cavaleiro, José A.S.

Chromones are a family of oxygen-containing heterocyclic compounds that have been shown particular relevant biological activity. In what concerns to 2-methylchromones, their reactivity is well-known and allowed to exploit many different kinds of chemical reactions. The acidic character of the 2-methyl group, due to the low electron density at C-2 caused by carbonyl group enable this class of compounds to underg...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Synthesis of novel 2-Butadienylchromone derivatives

Albuquerque, Hélio; Santos, Clementina M.M.; Esteves, Cátia; Silva, Artur; Cavaleiro, José

Chromones are a group of naturally occurring compounds with a benzoannelated ypyrone ring. A large number of chromone derivatives have been isolated from natural sources and a wide range of biological properties have been attribute to them, such as antifungal, anti-allergenic, antiviral, antitubulin, anti-hypertensive, anticancer and antioxidant activities.1 11 Studies with 2-styrylchromones demonstrated that t...

Data: 2012   |   Origem: Biblioteca Digital do IPB

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