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Strategies to enhance the removal of Fluoroquinolones

Amorim, Catarina L.; Maia, Alexandra S.; Moreira, Irina S.; van Loosdrecht, Mark C.M.; Tiritan, Maria E.; Castro, Paula M.L.

Fluoroquinolones (FQs) are broad-spectrum antibiotics that play an important role in the treatment of serious bacterial infections. Currently, several FQs are available but ciprofloxacin (CPF), ofloxacin (OFL) and norfloxacin (NOR) are amongst the most worldwide prescribed antibiotics. Antibiotics can reach wastewater treatment plants (WWTP) from different routes. Thus removal of these contaminants during the b...


Studies on enantioselective biodegradation of fluoxetine

Moreira, Irina S.; Ribeiro, Ana R.; Amorim, Catarina L.; Tiritan, Maria E.; Castro, Paula M. L.

Fluoxetine (FLX) is a chiral fluorinated pharmaceutical indicated mainly for treatment of depression and is one of the most dispensed drugs in the world. There is a clear evidence of environmental contamination with this drug. Granular sludge sequencing batch reactors (SBR) constitute a promising technology for the treatment of effluents containing micropollutants. In this study, a SBR was operated in order to...


Degradation of Fluoroquinolone Antibiotics and Identification of Metabolites/Tr...

Maia, Alexandra S.; Ribeiro, Ana R.; Amorim, Catarina L.; Barreiro, Juliana C.; Cass, Quezia B.; Castro, Paula M.L.; Tiritan, Maria E.

Antibiotics are a therapeutic class widely found inenvironmental matrices and extensively studied due to its persistence and implications for multi-resistant bacteria development. Degradation of four fluoroquinolone antibiotics, namely Ofloxacin (OFL), Norfloxacin (NOR), Ciprofloxacin (CPF) and Moxifloxacin (MOX), at 10 mg L-1 using a mixed bacterial culture, was assessed for 60 days. The assays were follow...


Aerobic granules in a sequencing batch bioreactor under fluoroquinolone shock l...

Amorim, Catarina L.; Maia, Alexandra S.; Mesquita, Raquel B. R.; Rangel, António O. S. S.; Tiritan, Maria E.; Castro, Paula M. L.

The growing occurrence of human and veterinary pharmaceuticals in the environment is causing increasing concern. Fluoroquinolones (FQs) are broad-spectrum antibiotics that play an important role in the treatment of serious bacterial infections. Antibiotics can reach wastewater treatment plants (WWTP) from different routes. Domestic effluents are considered the major contributor but effluents from pharmaceutical...


Effects of fluoxetine schock loadings in a aerobic granular sludge sequencing b...

Moreira, Irina S.; Ribeiro, Ana R.; Amorim, Catarina L.; Mesquita, Raquel B. R.; Rangel, António O. S. S.; Tiritan, Maria E.; Castro, Paula M. L.

Pharmaceuticals have received increasing attention as emerging organic pollutants due to their frequent occurrence in the environment and potential adverse effects on ecossistems and to human health. Pharmaceuticals may not be completely metabolized in the human body and can enter municipal sewage systems as the parent drug and as their “biologically active” metabolites. Some of these compounds cannot be easily...



Biodegradation of fluoroquinolones by single bacteria

Amorim, Catarina L.; Moreira, Irina S.; Maia, Alexandra; Tiritan, Maria E.; Castro, Paula M. L.


Studies on the biodegradation of fluoroanilines by a single microorganism

Amorim, Catarina L.; Carvalho, Maria F.; Afonso, Carlos M. M.; Castro, Paula M. L.

Aromatic amines are considered important environmental pollutants due to their toxic and recalcitrant properties. The widespread use of these compounds in the industry and agriculture has led to their release to soils and waters. Microbial degradation has been found to be the major mechanism to avoid the accumulation of these pollutants in the environment. Literature studies on the biodegradation of halogenate...


Degradation of fluoroanilines by the wild strain Labrys portucalensis

Amorim, Catarina L.; Carvalho, Maria F.; Afonso, Carlos M. M.; Castro, Paula M. L.

Aromatic amine compounds, many of them with halogenated substituents, constitute a major class of environmental pollutants that have been released into soil and water due to extensive use in industries and agriculture. Biodegradation has been found to be a major route for the removal of this kind of toxic and recalcitrant pollutants from the environment. Whereas the degradation of mono- and dichlorinated anilin...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia