Encontrados 4 documentos, a visualizar página 1 de 1
Conjugation of human topoisomerase 2A with small ubiquitin-like modifiers 2/3 i...
Agostinho, Marta; Santos, Vera; Ferreira, Fernando; Cardoso, Joana; Costa, Rafael; Pinheiro, Inês; Rino, José; Jaffray, Ellis; Hay, RonaldType 2 topoisomerases, in particular the A isoform in human cells, play a key role in cohesion and sister chromatid separation during mitosis. These enzymes are thus vital for cycling cells and are obvious targets in cancer chemotherapy. Evidence obtained in yeast and Xenopus model systems indicates that conjugation of topoisomerase 2 with small ubiquitin-like modifier (SUMO) proteins is required for its mitoti...
Human topoisomerase II\03B1 in chromatin based phenomena
Agostinho, Marta Elisa Dias, 1973-Tese de doutoramento em Ciências Biomédicas (Ciências Morfológicas), apresentada à Universidade de Lisboa através da Faculdade de Medicina, 2007
A DNA fragment of Desulfovibrio gigas genome containing replication origin rela...
Broco, Manuela; Oliveira, Solange; Silva, Gabriela; Agostinho, Marta; Rodrigues-Pousada, ClaudinaThe nucleotide sequence of a 10,772 base pair (bp) region from Desulfovibrio gigas genome was determined. This sequence, which is adjacent to the region containing the coding units for the metalloproteins rubredoxin-oxygen oxidoreductase (ROO) and rubredoxin, includes the flavodoxin gene. Additionally, it also contains four open reading frames (ORFs) related to genes frequently found in replication origin regio...
Molecular cloning of the gene encoding flavoredoxin, a flavoprotein from Desulf...
Agostinho, Marta; Oliveira, Solange; Broco, Manuela; Liu, M.Y.; LeGall, Jean; Rodrigues-Pousada, ClaudinaSulfate-reducing bacteria are rich in unique redox proteins and electron carriers that participate in a variety of essential pathways. Several studies have been carried out to characterize these proteins, but the structure and function of many are poorly understood. Many Desulfovibrio species can grow using hydrogen as the sole energy source, indicating that the oxidation of hydrogen with sulfite as the termina...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||