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Patch testing with 2.0% (0.60 mg/cm2) formaldehyde instead of 1.0% (0.30 mg/cm2...

Pontén, A; Aalto-Korte, K; Agner, T; Andersen, KE; Gimenez-Arnau, AM; Gonçalo, Margarida; Goossens, A; Johansen, JD; Le Coz, CJ; Maibach, HI

BACKGROUND: The currently used patch test concentration for formaldehyde is 1.0% (wt/vol) in water. However, clinical experience and previous studies suggest that 1.0% might be insufficient for detecting an optimized number of clinically relevant cases of contact allergy to formaldehyde. OBJECTIVES: To validate earlier patch test results for comparison of 1% (wt/vol) and 2% (wt/vol) formaldehyde in water, and t...


Hand eczema severity and quality of life: a cross-sectional, multicentre study ...

Agner, T; Andersen, KE; Brandão, FM; Bruynzeel, DP; Bruze, M; Frosch, P; Gonçalo, Margarida; Goossens, A; Le Coz, C; Rustemeyer, T; White, IR

BACKGROUND AND OBJECTIVES: Hand eczema is a chronic disease with negative impact on quality of life (QoL). In this study, QoL in hand eczema patients is assessed and related to age, sex, severity, and diagnostic subgroups. METHODS: A total of 416 patients with hand eczema from 10 European patch test clinics participated in the study. Data on QoL were obtained from a self-administered questionnaire using the Der...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia