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Fish scales patterning guiding hASC growth
Silva, Joana M.; Afonso, David Losa de Areia; Silva, Tiago H.; Volpato, F.; Motta, A.; Marques, A. P.; Mano, J. F.; Reis, R. L.; Migliaresi, C.Marine organisms and materials exhibit interesting properties for their use in biomedical applications, following biomimetic approaches [1,2]. For instance, the white seabass (Lates Calcarifer) scales exhibit a very interesting pattern, which inspire their use as a guiding platform for cellular growth, in a tissue regeneration approach. Moreover, fish scales are composed of hydroxyapatite and type I collagen fi...
Fish scales as model for osteogenic cells culture
Afonso, David Losa de AreiaDissertação de mestrado integrado em Engenharia Biomédica (área de especialização em Biomateriais, Reabilitação e Biomecânica) ; Considering the fish scales composition of hydroxyapatite and type I collagen fibrils, the organized and regular pattern of the scales, and also their capability to provide a form of armor plating to protect fish from injury and disease transmission, its potential biomedical applicat...
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