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A Dislexia em Tese: Atas do Encontro Nacional

O simpósio Dislexia em Tese visa apresentar resultados de experiências/reflexões científicas (mestrado e/ou doutoramento) sobre dislexia/leitura com um duplo objetivo: promover o conhecimento dos educadores sobre a dificuldade de aprendizagem específica na leitura (Dislexia) e auxiliar os alunos/cidadãos disléxicos no entendimento das suas características. Sumariamente, a dislexia, as perturbações que podem est...

Enantioselective Degradation of Enantiomers of Fluoxetine Followed by HPLC- FD

Environmental fate assessment of chiral pharmaceuticals is an important issue and little information is known about enantioselectivity in the environment. This kind of information is important for regulamentation of pharmaceutical industry and chiral switching processes. Fluoxetine (FLX), an anti-depressant worldwide used, is a chiral pharmaceutical prescribed in racemic form, and its main metabolite norfl...

Enantioselective Determination of Fluoxetine and Norfluoxetine in Wastewater

Microbial degradation of chiral compounds during wastewater treatment processes can be enantioselective and needs chiral analytical methodology to discriminate the biodegradation of both enantiomers. An enantioselective HPLC-FD method was developed and validated to monitor the degradation of fluoxetine (FLX) enantiomers by wastewater and the possible formation of its metabolite norfluoxetine (NFLX). The So...

Intramolecular C–H insertion catalyzed by dirhodium(II) complexes using CO2 as ...

In this work, the intramolecular C–H insertion of diazoacetamides catalyzed by dirhodium(II) complexes and using CO2 as solvent is disclosed. The expected lactams were obtained in yields over 97%. The asymmetric intramolecular C–H insertion was also achieved and the β-lactam 14 was obtained in >97% yield and 65% ee using the chiral dirhodium(II) catalyst Rh2(S-PTTL)4. Finally, the dirhodium(II) complex Rh2(OAc)...

Biodegradation of chiral pharmaceuticals by an activated sludge consortium foll...

Biodegradation tends to be enantioselective in contrast to abiotic degradation and it is necessary enantioselective analytical methods to quantify the enantiomeric fraction of chiral pharmaceuticals in the environment for correct risk assessment. In this work, we developed HPLC-FD methods to follow the biodegradation of four beta-blockers: alprenolol , propranolol , metoprolol and atenolol and the antidepressan...

Lajes fungiformes. Contribuições para a compreensão do seu comportamento

Perfil alimentar do doente com excesso de peso

[abstract] ; [resumo]

Comparing clustering and partitioning strategies

In this work we compare balance and edge-cut evaluation metrics to measure the performance of two well-known graph data-grouping algorithms applied to four web and social network graphs. One of the algorithms employs a partitioning technique using Kmetis tool, and the other employs a clustering technique using Scluster tool. Because clustering algorithms use a similarity measure between each graph node and part...

[Prefácio a] "100 experiências de química orgânica"

Biodegradation of Beta-Blockers and Fluoxetine followed by a Chiral HPLC-FD

Despite of the massive publications concerning pharmaceuticals in the environment, the problematic related with chiral compounds and enantioselective degradation are still largely unknown [1]. Enantiomers have different interactions with enzymes, receptors and other chiral molecules, leading to different biological activities. Thus, biodegradation tends to be enantioselective in contrast to abiotic degradation....