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99mTc Auger electrons for targeted tumour therapy : a review
Adriana Alexandre dos Santos Tavares; João Manuel Ribeiro da Silva TavaresPurpose: Targeted radiotherapy using Auger electrons presents multiple advantages and challenges. The advantageous characteristics of this type of radiotherapy can explain the growing interest in these specific electrons for cancer therapy. During the last decade, Technetium-99m (99mTc) has been used as an imaging agent and only recently has it been analyzed as a potential therapeutic agent. This paper aims to ...
Evaluating 99mTc Auger electrons for targeted tumor radiotherapy by computation...
Adriana Alexandre dos Santos Tavares; João Manuel Ribeiro da Silva TavaresPurpose: Technetium-99m (99mTc) has been widely used as an imaging agent but only recently has been considered for therapeutic applications. This study aims to analyze the potential use of 99mTc Auger electrons for targeted tumor radiotherapy, by evaluating the DNA damage and its probability of correct repair and by studying the cellular kinetics, following 99mTc Auger electrons irradiation in comparison to Iod...
Princípios gerais de culturas de células e citometria de fluxo para avaliação d...
Adriana Alexandre dos Santos Tavares; João Manuel R. S. TavaresThis report aims to explain in the basic principles of cells culture and flow citometry for the study of ionizing radiation effects on cells culture. Thus, subjects such as cells culture type and advantages/disadvantages of cells culture are explained. Additionally, basic principles of flow citometry, as well as, its applicability for the study of ionizing radiation effects on cell culture are also presented. ;...
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