A 50-year-old post-menopausal recipient of a kidney allograft with bone pain, osteoporosis, persistent hypercalcaemia and elevated parathormone (PTH) levels, despite a satisfactory graft function, was treated with bisphosphonates and cinacalcet starting, respectively, 5 and 6 months after renal transplantation (RT). Sixteen months after treatment, there was improvement of bone mineral density (BMD) measured by ...
Nas últimas décadas, houve um declínio marcado da incidência global da insuficiência renal aguda (IRA) associada a causas obstétricas nos países desenvolvidos, devendo-se à melhoria significativa dos cuidados perinatais e à diminuição do número de abortos sépticos. Não obstante, a IRA ainda ocorre, tendo uma mortalidade elevada durante o período agudo, não sendo rara a progressão para insuficiência renal termin...
Com a Transplantação Renal regista-se recuperação da fertilidade. A exposição a fármacos imunossupressores, como a prednisona, a ciclosporina, a azatioprina e o tacrolimus não está associada com um aumento da incidência de malformações congénitas. A Imunossupressão, particularmente com a ciclosporina, está relacionada com recém-nascidos com baixo peso ao nascer. Doentes transplantados têm um risco aumentado de ...
To study the effect of the correction of post-transplantation Hypophosphatemia on mineral metabolism.15 patients with renal transplants for 3 to 12 months, Serum Creatinine "177 micmol/1, were treated with oral phosphorus (P) for persistent hypophosphatemia.3 periods of blood and urine collection at intervals of 3 weeks. T1 under basal treatment with oral P, T2 after 3 weeks off medication with P, Ca, or P bind...
Iron deficiency occurs often in patients with recombinant human Erythropoietin (rhEPO) therapy in chronic renal failure (CRF) associated anemia. We have studied 10 patients with CRF on regular hemodialysis (HD), female = 8, male = 2, average age = 49 [32 to 72], time on HD 44.2 +/- 25.0 months. Before starting rhEPO, the mean hemoglobin value was 7.36 +/- 1.29 gr/dl, the mean ferritin 695.4 +/- 276.0 ng/ml, the...
Percutaneous Nephrostomy (P.N.) has been traditionally used by Urologists. The authors seek to demonstrate the interest of its mastering by members of Nephrology teams, by reviewing 27 cases of unilateral or bilateral P.N. performed in a Nephrology unit from 1983 to 1991. The single most frequent indication for P.N. was Acute or Chronic Renal Insufficiency of obstructive etiology (21 cases), followed by infecte...
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