Encontrados 27 documentos, a visualizar página 1 de 3

Fluorescence studies of 2-quinolinones and coumarins including peptide derivati...

Photophysical properties of 2-quinolinones and coumarins, including peptide derivatives, were determined. Fluorescence emission and anisotropy measurements of compounds incorporated in lipid vesicles were performed. Our studies indicate that these compounds may be used as fluorescent probes for peptides and lipid membranes.

Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes

Prova tipográfica ; A 3-(phenanthren-9-yl)-1H-indole-2-carboxylic acid (2) obtained from the cleavage of the methyl ester of the methyl 3-(phenanthren-9-yl)-1H-indole-2-carboxylate (1) was inserted into a peptide containing the RGD sequence. The GGRGDG peptide sequence was prepared by solid phase synthesis and coupled to compound (2), using diisopropylcarbodiimide (DIC) and 1-hydroxybenzotriazole (HOBt) in DMF...

Nanoliposomes for encapsulation and delivery of the potential antitumoral methy...

A potential antitumoral fluorescent indole derivative, methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate, was evaluated for the in vitro cell growth inhibition on three human tumor cell lines, MCF-7 (breast adenocarcinoma), A375-C5 (melanoma), and NCI-H460 (non-small cell lung cancer), after a continuous exposure of 48 h, exhibiting very low GI50 values for all the cell lines tested (0.25 to 0.33 µM)...

Interaction of new fluorescent 2-quinolinone and coumarin derivatives with phos...

RICI4 - Book of Abstracts

Fluorescence studies of 3-amino-4-phenylquinolin-2-one in solution and in lipid...

Book of Abstracts - QO-CP 090

Nanoliposomes for encapsulation and delivery of the potential antitumoral methy...

Studies of encapsulation of new antitumoral fluorescent compounds in nanoliposo...

Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes

Studies of encapsulation of a new potential antitumoral indole derivative in na...

Fluorescence properties of a potential antitumoral benzothieno[3,2-b]pyrrole in...

Fluorescence properties of the antitumoral methyl 3-(benzo[b]thien-2-yl)-benzothieno[3,2-b]pyrrole-2-carboxylate (BTP) were studied in solution and in lipid bilayers of dipalmitoyl phosphatidylcholine (DPPC), dioleoyl phosphatidylethanolamine (DOPE) and egg yolk phosphatidylcholine (Egg-PC). BTP presents good fluorescence quantum yields in all solvents studied (0.20 ≤ ΦF ≤ 0.32) and a bathochromic shift in pola...