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Molecular and cytogenetic characterization of expanded B-cell clones from multi...
Henriques, A; Rodriguez-Caballero, A; Criado, I; Langerak, AW; Nieto, WG; Lecrevisse, Q; Gonzáles, M; Cortesão, E; Paiva, A; Almeida, J; Orfão, AChronic antigen-stimulation has been recurrently involved in the earlier stages of monoclonal B-cell lymphocytosis, chronic lymphocytic leukemia and other B-cell chronic lymphoproliferative disorders. Among these individuals, expansion of ≥2 B-cell clones has been frequently reported; potentially, such coexisting clones have a greater probability of interaction with common immunological determinants. Here, we c...
Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders
Correia, C.T.; Conceição, I.C.; Oliveira, B.; Coelho, J.; Sousa, I.; Sequeira, A.F.; Almeida, J.; Café, C.; Duque, F; Mouga, S.; Roberts, W.; Gao, K.Validating the potential pathogenicity of copy number variants (CNVs) identified in genome-wide studies of autism spectrum disorders (ASD) requires detailed assessment of case/control frequencies, inheritance patterns, clinical correlations, and functional impact. Here, we characterize a small recurrent duplication in the annexin A1 (ANXA1) gene, identified by the Autism Genome Project (AGP) study.
A preocupação com o excesso de peso dos filhos enquanto determinante das atitud...
Viana, Victor; Almeida, J.P.; Silva, Diana; Guardiano, M.; Espinheira, C.; Guerra, António[abstract] ; [resumo]
Ansiedade Social na Infância e Pré-Adolescência: Adaptação para o Português de ...
Martins, A.C; Almeida, J.P.; Viana, VictorThe Social Anxiety Scale for Children (revised form) - SASC-R evaluates the experience of social anxiety and avoidance felt by children and pre-adolescents in the context of relationship with their peers. This study aims to validate the Portuguese version of the SASC-R by confirmatory factor analysis using the structure proposed by the authors of the original scale. In a survey donewith 486 children between the...
VULVAR LICHEN SCLEROSUS – A REVIEW OF 208 CASES
Torres, Ermelindo; Interno(a) do Internato Complementar de Dermatologia e Venereologia/Resident Dermatology and VenereologyIntroduction: Lichen sclerosus (LS) is a chronic idiopathic inflammatory disease that preferentially affects the anogenital region and postmenopausal Caucasian women. Aims: Retrospective characterization of patients with vulvar LS diagnosed and treated at our Department (Vulvar Pathology Consultation), between 1986 and 2004. Material and Methods: A total of 208 Caucasians women were included in the study. We co...
Doença Pulmonar Obstrutiva Crónica em Portugal: estudoPneumobil (1995) e estudo...
Cardoso, J; Ferreira, JR; Almeida, J; Santos, JM; Rodrigues, F; Matos, MJ; Gaspar, MBACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) has been a leading cause of morbidity and mortality worldwide, over the years. In 1995, the implementation of a respiratory function survey seemed to be an adequate way to draw attention to neglected respiratory symptoms and increase the awareness of spirometry surveys. By 2002 there were new consensual guidelines in place and the awareness that prevalenc...
A -mercaptoethanol-modified enzyme-linked immunosorbent assay for diagnosis of...
Barral-Veloso, L.; Semiao-Santos, S. J.; de Andrade, P. P.; de Melo, M. A.; Martins, L.; Marinho, A. A.; de Almeida, J. A. A.; Cardoso, L.Two immunoglobulin G enzyme-linked immunosorbent assay (ELISA) versions using whole promastigotes of Leishmania infantum (syn. Leishmania chagasi) treated either with β-mercaptoethanol (β-ME-ELISA) or trypsin (TRYP-ELISA) as antigens were developed for the diagnosis of canine visceral leishmaniasis (CVL). By comparison with the direct agglutination test (DAT; 100%, 31/31; 95% confidence interval [CI]: 86.3–100%...
Museu da Pessoa – arquitectura
Almeida, J. João; Rocha, J. Gustavo; Henriques, P. Rangel; Moreira, Sónia; Simões, AlbertoÉ conhecido o extremo valor patrimonial e sociológico das Histórias de Vida. No entanto, apesar do encanto irresistíveldas histórias, trata-se de um património em rápido desaparecimento.O Museu da Pessoa é um arquivo fundamentalmente acessível pela Internet, que apresenta um conjunto de especificidades:
The “montado”: determinant factor affecting the carcass characteristics and the...
Freitas, A.B.; Neves, J.; Nunes, J.T.; Almeida, J.A.The objective of this study was to assess the effect of the finishing system (under montanheira or with commercial feed) on carcass characteristics and dry cured-ham of Alentejano pigs. 24 pigs were fattening until 130 kg LW under montanheira and 24 pigs were fattening with commercial feed. Carcasses of pigs fattened under the montanheira system were slightly heavy (98,38 vs 96,13 kg), with significantly higher...
A formação docente para a prática inclusiva no Curso de Pedagogia da Universida...
Almeida, J.; Chaleta, E.; Oliveira, VVários elementos são fundamentais para o sucesso de uma escola inclusiva. Para que esta seja uma realidade é fundamental a mudança de concepção de educação, de escola, de prática pedagógica, de currículo, de avaliação, etc., mas nenhum desses elementos surtirá efeito se não houver a formação e a capacitação dos professores para a prática de uma Educação Inclusiva (UNESCO & MEC-Espanha, Declaração de Salamanca, ...
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