Chronic myeloid leukemia (CML) is rare in the pediatric population, accounting for 2-3% of childhood leukemia cases, with an annual incidence of one case per million children. The low toxicity profile of imatinib mesylate has led to its approval as a front-line therapy in children for whom interferon treatment has failed or who have relapsed after allogeneic transplantation. We describe the positive responses o...
We characterise the structure of fibrous materials: papers and nonwovens by diffraction and transmission of light. This allows the measurement of the fibres orientation distribution of the sample as a whole or for the surfaces using replicas. Applications of the methods are demonstrated in the case of paper for the control of the curl tendency and for two kinds of nonwoven materials, one used in the tailoring o...
Plot-scale overland flow experiments were conducted to evaluate the efficiency of streamside management zones (SMZs) in retaining herbicides in runoff generated from silvicultural activities. Herbicide retention was evaluated for five different slopes (2, 5, 10, 15, and 20%), two cover conditions (undisturbed O horizon and raked surface), and two periods under contrasting soil moisture conditions (summer dry an...
O presente trabalho visou avaliar a diversidade de crisomelídeos-praga associados às culturas do feijão comum (Phaseolus vulgaris (L. ) e melancia [Citrullus lanatus (Thunb.) Matsum & Nakai], em Rondônia. A coleta de insetos foi realizada semanalmente. Os espécimes presentes foram observados em microscópio estereoscópico, contados e classificados em morfoespécies de acordo com as suas características morfológic...
BRCA1 mutations are known to be responsible for the majority of hereditary breast and ovarian cancers in women with early onset and a family history of the disease. In this paper we present a mutational survey conducted in 47 Brazilian patients with breast/ovarian cancer, selected based on age at diagnosis, family history, tumor laterality, and presence of breast cancer in male patients. All 22 coding exons and...
1993
1987
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