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Mechanisms of tolerance induction to foreign proteins

Água-Doce, Ana

Tese de doutoramento, Ciências Biomédicas (Imunologia), Universidade de Lisboa, Faculdade de Medicina, 2013 ; Several immune mediated diseases, such as autoimmunity and allergy or transplant rejection are consequence of inappropriate immune responses towards specific antigens. The therapeutic induction of robust immune tolerance has, therefore been considered the Holy Grail of immunology since the pioneering w...


Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthri...

Duarte, Joana; Agua-Doce, Ana; Oliveira, Vanessa G.; Fonseca, João Eurico; Graça, Luís

©2010 Duarte et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ; Background: Rheumatoid Arthritis (RA) is a chronic immune mediated disease associated with deregulation of many cell types. It has been reported that diffe...


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