Detalhes do Documento

trans-Acting factors and cis elements involved in glucose repression of arabina...

Autor(es): Sá-Nogueira, Isabel de cv logo 1 ; Inácio, José Manuel cv logo 2

Data: 2007

Identificador Persistente: http://hdl.handle.net/10362/4203

Origem: Repositório Institucional da UNL


Descrição
Journal of Bacteriology (Nov 2007) 8371-8376 In Bacillus subtilis, the synthesis of enzymes involved in the degradation of arabinose-containing polysaccharides is subject to carbon catabolite repression (CCR). Here we show that CcpA is the major regulator of repression of the arabinases genes in the presence of glucose. CcpA acts via binding to one cre each in the promoter regions of the abnA and xsa genes and to two cres in the araABDLMNPQ-abfA operon. The contributions of the coeffectors HPr and Crh to CCR differ according to growth phase. HPr dependency occurs during both exponential growth and the transitional phase, while Crh dependency is detected mainly at the transitional phase. Our results suggest that Crh synthesis may increase at the end of exponential growth and consequently contribute to this effect, together with other factors.
Tipo de Documento Artigo
Idioma Inglês
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