Author(s):
Folgosa, Filipe dos Santos 
Date: 2008
Persistent ID: http://hdl.handle.net/10362/1774
Origin: Repositório Institucional da UNL
Document details
Structural and mechanistic studies of iron containing proteins
Description
Dissertação apresentada para obtenção do Grau de Doutor em Bioquímica, ramo de Bioquímica-Física, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia Over the last few decades a large effort has been done in the structural biochemistry field. This effort is based on the study of some proteins, namely metalloproteins, that contain cofactors and/or active sites with metal ions in their constitution. This thesis will focus on different studies performed in metalloproteins that contain non-heme iron centers. An important point is their relation to oxygen and reactive oxygen species. To perform these studies, fast kinetic techniques were used coupled to spectroscopic techniques, such as Electronic Paramagnetic Resonance (EPR), Mössbauer and UVVisible.
Dissertação apresentada para obtenção do Grau de Doutor em Bioquímica, ramo de Bioquímica-Física, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia Over the last few decades a large effort has been done in the structural biochemistry field. This effort is based on the study of some proteins, namely metalloproteins, that contain cofactors and/or active sites with metal ions in their constitution. This thesis will focus on different studies performed in metalloproteins that contain non-heme iron centers. An important point is their relation to oxygen and reactive oxygen species. To perform these studies, fast kinetic techniques were used coupled to spectroscopic techniques, such as Electronic Paramagnetic Resonance (EPR), Mössbauer and UVVisible.
Document Type
Doctoral Thesis
Language English
Advisor(s) Tavares, Pedro
Language English
Advisor(s) Tavares, Pedro
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