Multiple cutaneous reticulohistiocytomas in a patient with rheumatoid arthritis

• Author(s): Vieira, R ; Robalo-Cordeiro, M ; Mariano, A ; Reis, JP ; Tellechea, O ; Figueiredo, A
• Date: 2004
• Persistent ID: http://hdl.handle.net/10400.4/364
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Artrite Reumatóide; Doenças da Pele
• Document Type: Article
• Language: English

Description

A 64-year-old woman with a long-standing peripheral symmetric polyarthritis with positive rheumatoid serology was evaluated for multiple asymptotic papulonodules of fingers, mentum, lower lip, ears, and eyelids. Histopathologic examination showed a dermal infiltrate composed of histiocytes, multinucleate giant cells with ground-glass cytoplasm, and lymphocytes, suggestive of reticulohistiocytoma. The possibilities of multicentric reticulohistiocytosis with positive rheumatoid serology or coexistence of multiple cutaneous reticulohistiocytomas and rheumatoid arthritis are discussed.