Terapêutica farmacológica da doença de Cushing

• Author(s): Paiva, I ; Ribeiro, C
• Date: 2005
• Persistent ID: http://hdl.handle.net/10400.4/30
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Síndrome de Cushing
• Document Type: Article
• Language: Portuguese

Description

The curative treatment of Cushing's disease is surgery, mainly transphenoidal surgery. The cure probability is high and the risks or complications are few. However, pharmacotherapy is necessary while localisation of the secreting tumour is not achieved, when there is persistence of hypercortisolism after surgery, or while waiting for effectiveness of radiotherapy. We review the existing drugs, their characteristics, mechanisms of action, doses and specific indications.