3-Aminopyrroles and their application in the synthesis ofpyrrolo[3,2-d]pyrimidi...

• Autor(es): Salaheldin, Abdellatif M. ; Campos, Ana M. F. Oliveira ; Rodrigues, Lígia M.
• Data: 2008
• Identificador Persistente: http://hdl.handle.net/1822/8432
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): 3-Aminopyrrole,; Pyrrolo[3,2-d]pyrimidine; 9-deazapurines; β-enaminonitriles; Thorpe-Ziegler cyclization
• Tipo de Documento: Artigo
• Idioma: Inglês

Descrição

3-Aminopyrrole derivatives have been synthesized from 3-anilino-2-cyanoacrylonitrile using Thorpe-Ziegler cyclization. These substituted pyrroles are readily converted into 5H-pyrrolo[3,2- d]pyrimidine (9-deazapurines).