Electrosynthesis of nitrogen heterocycles using environmentally friendly method...

• Author(s): Chaminade, X. ; Duñach, E. ; Esteves, Ana Paula ; Medeiros, Maria José ; Neves, C. S. S. ; Olivero, S.
• Date: 2009
• Persistent ID: http://hdl.handle.net/1822/25643
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Ethanol; Cyclisation; Nickel(II) complexes; Electroreduction; Heterocycles
• Document Type: Article
• Language: English

Description

Cyclic voltammetry and constant-current electrolysis in a one-compartment cell with a sacrificial anode has been used to study the indirect electroreduction of N-allyl- -haloamides by electrogenerated Ni(I) complexes conducted inN,N-dimethylformamide (DMF) and acetonitrile (ACN) and the resultswere compared with those obtained in protic solvents such as EtOH and EtOH–H2O mixtures. It was observed that the indirect electrochemical reduction of N-allyl- -haloamides led to the corresponding lactams and the yields and selectivities obtained in EtOH and EtOH–H2O were much better than those obtained in DMF or ACN.