Electrochemical catalytic cyclization reactions using environmentally friendly ...

• Author(s): Duñach, E. ; Medeiros, M. J. ; Olivero, S.
• Date: 2013
• Persistent ID: http://hdl.handle.net/1822/24707
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Cyclization; Nickel(II) complex; Electroreduction; Heterocycles; Ethanol solvent
• Document Type: Article
• Language: English

Description

The electrochemical intramolecular cyclisation of bromoalkoxylated derivatives 1 was carried out using Ni(II) complexes as the catalysts in ethanol solutions by constant-current electrolysis in one-compartment cell in the absence of sacrificial anodes as an environmentally friendly system. The reduction of the substrates proceeds via one-electron cleavage of the carbon–bromine bond to form radical-type intermediates that undergo cyclisation to afford cyclic ethers in moderate to good yields.