Electrochemical catalytic cyclization reactions using environmentally friendly ...

• Autor(es): Duñach, E. ; Medeiros, M. J. ; Olivero, S.
• Data: 2013
• Identificador Persistente: http://hdl.handle.net/1822/24707
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): Cyclization; Nickel(II) complex; Electroreduction; Heterocycles; Ethanol solvent
• Tipo de Documento: Artigo
• Idioma: Inglês

Descrição

The electrochemical intramolecular cyclisation of bromoalkoxylated derivatives 1 was carried out using Ni(II) complexes as the catalysts in ethanol solutions by constant-current electrolysis in one-compartment cell in the absence of sacrificial anodes as an environmentally friendly system. The reduction of the substrates proceeds via one-electron cleavage of the carbon–bromine bond to form radical-type intermediates that undergo cyclisation to afford cyclic ethers in moderate to good yields.