Synthesis of glycoconjugates containing a 1,2,3-triazole unit

• Autor(es): Cunha, S. ; Pereira, S. ; Malheiro, M. ; Rodrigues, Lígia M. ; Campos, Ana M. F. Oliveira ; Esteves, Ana Paula
• Data: 2013
• Identificador Persistente: http://hdl.handle.net/1822/22443
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): Glycoconjugates; Click chemistry; Triazole; Alkynyl esters
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

The preparation of several alkynyl esters, derived from amino acids, coumarins and an alkynyl derivative of acetylated D-glucose is described. Eight new glycoconjugates containing the 1,2,3-triazole unit were obtained, by a click approach from the above referred alkynyl derivatives with tetracetyl-beta-D-glucosylazide, prepared in situ from alpha-acetobromoglucose.