General synthetic approach to 2-phenolic adenine derivatives

• Author(s): Correia, C. ; Carvalho, M. Alice ; Rocha, Ashly ; Proença, M. Fernanda R. P.
• Date: 2012
• Persistent ID: http://hdl.handle.net/1822/22046
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Nucleobases; Phenols; Condensations; Aldehydes; Ring closure
• Document Type: Article
• Language: English

Description

A simple and general “one pot” procedure for the synthesis of 2,9-diarylpurines with one or multiple hydroxyl groups in the 2- aryl unit is described, from the reaction of 5-amino-4-amidinoimidazoles with phenolic aldehydes.