Development of a temporary marker for peptides

• Author(s): Gonçalves, M. Sameiro T. ; Maia, Hernâni L. S.
• Date: 2003
• Persistent ID: http://hdl.handle.net/1822/1952
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Azo dyes; Label; Amino acids; Temporary marker
• Document Type: Article
• Language: English

Description

3-[(N,N-dimethylaminophenyl)-4'-diazenyl]-benzoic acid was coupled with several amino acid esters and the product further acylated with Boc. The material thus obtained was then submitted to cleavage by electrolysis and nucleophilic attack in order to evaluate the possibility to use this chromophore as a temporary marker.