Document details

Michaelis-menten kinetics: explicit dependence of substrate concentration on re...

Author(s): Freitas, A. Cristina cv logo 1 ; Malcata, F. Xavier cv logo 2

Date: 1993

Persistent ID: http://hdl.handle.net/10400.14/6700

Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa


Description
The nonlinear dependence of the rate expressions associated with enzymecatalysed reactions on the concentration of substrate implies that the corresponding integrated form of the substrate mass balance in a batch reactor cannot be expressed as an explicit function of time..This paper addresses this problem for the classical case of Michaelis—Menten kinetics by providing a self-pacing exploration of the characteristics of a Taylor expansion of the substrate concentration on time. The accuracy of such an approximation is discussed. The procedure presented is appropriate to model situations of technological and practical interest.
Document Type Article
Language English
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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento EU