New syntheses of potential biologically active xanthones and benzoxanthones

• Author(s): Rocha, Djenisa H. A. ; Leal, Stephanie B. ; Seca, Ana M. L. ; Pinto, Diana C. G. A. ; Silva, Artur M. S.
• Date: 2013
• Persistent ID: http://hdl.handle.net/10400.3/2935
• Origin: Repositório da Universidade dos Açores
• Subject(s): Xanthones; Synthesis; Benzoxanthones
• Document Type: Conference Object
• Language: English

Description

10º Encontro Nacional de Química Orgânica e 1º Simpósio Luso-Brasileiro de Química Orgânica, Lisboa, 4-6 Setembro de 2013. The synthesis of xanthones, adequately functionalized for a specific application, is a challenging task. In this presentation, will be disclosed our recent studies with this unique family of compounds, namely the one-pot photoinduced electrocyclisation of (E)-3-styrylflavones 1 and in situ oxidation of cycloadducts to give 5-phenyl-7H-benzo[c]xanthen-7-one derivatives 2,3a and aromatization studies of (E)-3-aryl-4-benzylidene-8-hydroxy-3,4-dihydro-1H-xanthene-1,9(2H)-diones 33b into 4-benzyl-1,8-dihydroxy-3-phenyl-9H-xanthen-9-one derivatives 4.