Composition and biological activity of the essential oil peruvian lantana camara

• Autor(es): Benites, Julio ; Moiteiro, Cristina ; Miguel, Graça ; Rojo, Leonel ; Lopez, José ; Venâncio, Florência ; Ramalho, Luís ; Feio, Sónia ; Dandlen, Susana ; Casanova, Hugo ; Torres, Ivan
• Data: 2009
• Identificador Persistente: http://hdl.handle.net/10400.9/585
• Origem: Repositório do LNEG
• Assunto(s): Antibacterial; Antioxidant; Anti-inflammatory; Carvone; 13C-NMR; Essential oil composition; GC-MS; Lantana camara; Limonene; Verbenaceae
• Tipo de Documento: Texto de Periódico
• Idioma: Inglês

Descrição

The composition of the essential oil from Lantana camara L. (Verbenaceae) obtained by hydrodistillation of the aerial parts was examined by GC, GC/MS, and 13C-NMR. The GC analysis showed that carvone is the most abundant monoterpene 75.9%, together with limonene 16.9%, accounting for 92.8% of the oil. The major components were also tested by 13C-NMR analysis of the essential oil. The L. camara oil was assayed against several microorganisms, showing moderate antibacterial activity against the human pathogen Staphylococcus aureus (MIC  200  μg/ml). High antioxidant activity evaluated by the Trolox equivalent antioxidant capacity assay (TEAC) was found (29.0  mmol Trolox/kg) and relative low anti-inflammatory activity due to its weak ability for inhibiting lipoxygenase (IC50  =   81.5  μg/ml).