Possible respiratory infection due to Aspergillus in workers from swineries and...

• Autor(es): Sabino, Raquel ; Faísca, Vanessa Mateus ; Viegas, Susana ; Veríssimo, C. ; Viegas, Carla
• Data: 2012
• Identificador Persistente: http://hdl.handle.net/10400.21/2482
• Origem: Repositório Científico do Instituto Politécnico de Lisboa
• Assunto(s): Environmental health; Occupational health; Aspergillus; Poultry; Swinery; Asthma; Lung function; Respiratory disease; Allergic disease
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

Recent epidemiologic studies clearly outline the link between fungal sensibilization and exarcebations of asthma, leading to increased morbidity and mortality. Amongst the filamentous fungi, Aspergillus scpecies have been strongly linked with exarcebations of asthma and other respiratory allergic diseases. Particles of approximately 1 to 4 pm are deposited in the lower respiratory tract. Therefore, conidia of A. fumigatus are small enough to traverse the terminal respiratory airways and reach the pulmonary alveoli, whereas the larger conidia of some other Aspergillus species, such as A. flavus and A. niger, tend to be deposited in the paranasal sinuses and upper airways. Exposute to environmental fungal spores has been associated with worsening asthma symptoms, lung function, hospital admissions and asthma-related deaths.