Strength, muscle quality and functional capacity in liver transplanted familial...

• Autor(es): Tomás, Mª Teresa ; Santa-Clara, Helena ; Monteiro, Estela ; Pimenta, N. ; Cabri, Jan ; Freire, António ; Barroso, Eduardo
• Data: 2009
• Identificador Persistente: http://hdl.handle.net/10400.21/1522
• Origem: Repositório Científico do Instituto Politécnico de Lisboa
• Assunto(s): Fisioterapia; Reabilitação; Polineuropatia amiloidótica familiar; Transplante de órgãos; Fígado
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

Liver transplantation is the unique treatment for several end stage diseases. Familial Amiloidotic Polineuropathy (FAP) is a neurodegenerative disease related with systemic deposition of amyloidal fibre mainly on peripheral nervous system, clinically translated by an autonomous sensitive-motor neuropathy with severe functional limitations in some cases. The unique treatment for FAP disease is a liver transplant with a very aggressive medication to muscle metabolism and force production. To our knowledge there are no quantitative characterizations of body composition, strength or functional capacity in this population. The purpose of this study was to compare levels of specific strength (isometric strength adjusted by lean mass or muscle quality) and functional capacity (meters in 6 minutes walk test) between FAP patients after a liver transplant (4.1±2 months after transplant surgery) (FAPT) and a healthy group (HG).