From juvenile parkinsonism to encephalitis lethargica, a new phenotype of post-...

• Author(s): Beleza, P ; Soares-Fernandes, J ; Jordão, MJ ; Almeida, F
• Date: 2008
• Persistent ID: http://hdl.handle.net/10400.23/448
• Origin: Repositório Científico do Hospital de Braga
• Subject(s): Doença de Parkinson Pós-Encefalítica; Infecções por Streptococcus; Adolescente
• Document Type: Article
• Language: English

Description

We report the case of a 16-year-old boy presented with a mild akinetic-rigid parkinsonism shortly after a post-streptococcal infection. After stopping corticoids, he had a rapid neurological deterioration to a fatal encephalitis lethargica-like syndrome. Serum analysis demonstrated consistently elevated anti-streptolysin-O. This case illustrates a new severe phenotype in the spectrum of the post-streptococcal disorders. This etiology should be considered in the differential diagnosis of a movement disorder with a rapid detrimental evolution.