Neuroimaging findings in alcohol-related encephalopathies

• Autor(es): Zuccoli, G ; Siddiqui, N ; Cravo, I ; Bailey, A ; Gallucci, M ; Harper, C
• Data: 2010
• Identificador Persistente: http://hdl.handle.net/10400.10/822
• Origem: Repositório do Hospital Prof. Doutor Fernando Fonseca
• Assunto(s): Alcoholism; Encephalopathies; Diagnostic imaging
• Tipo de Documento: Artigo
• Idioma: Inglês

Descrição

OBJECTIVE: Our aim was to review the emergent neuroimaging findings of alcohol-related CNS nontraumatic disorders. Alcohol (ethanol) promotes inflammatory processes, increases DNA damage, and creates oxidative stress. In addition, the accompanying thiamine deficiency may lead to Wernicke encephalopathy. Associated changes in serum osmolarity may lead to acute demyelination. CONCLUSION: Alcohol-related encephalopathies can be life-threatening conditions but can be prevented or treated, if recognized.