Successful pregnancy in a severely hypoxemic patient with pulmonary alveolar pr...

• Author(s): Belchior, I. ; Cerdeira, A. ; Santos, M. ; Braga, J. ; Aragâo, I. ; Martins, A.
• Date: 2011
• Persistent ID: http://hdl.handle.net/10400.16/869
• Origin: Repositório Científico do Centro Hospitalar do Porto
• Subject(s): Pregnancy; Pulmonary alveolar proteinosis; Pulmonary lavage; Respiratory failure; Gravidez; Proteinose alveolar Pulmonar; Lavagem pulmonar; Insuficiência respiratória
• Document Type: Article
• Language: English

Description

Abstract Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by abnormal accumulation of a lipoproteinaceous material in the alveoli, which may lead to respiratory failure and has an associated high risk for infections. The mainstay treatment for PAP is whole lung lavage. A pregnant woman, previously diagnosed with primary PAP, the most common form of PAP, was admitted with dyspnea and worsening respiratory function. In one month period, a wholelung bronchopulmonary lavage was performed twice, with clinical and functional improvement. Pregnancy was carried to term and a healthy baby was delivered. The mechanisms of respiratory impairment are discussed as well as treatment options and response. Resumo A proteinose alveolar pulmonar (PAP) é uma doença rara caracterizada pela acumulação anormal de material lipoproteináceo nos alvéolos, que pode levar a insufi ciência respiratória, estando associada a um risco elevado de infecções. O tratamento gold-standard da PAP é a lavagem pulmonar total.