Author(s):
LIMA, M. 
; PINTO, L. ; DOS ANJOS TEIXEIRA, M. ; CANELHAS, A. ; MOTA, A. ; CABEDA, J.M. ; SILVA, C. ; QUEIROS, M.L. ; FONSECA, S. ; SANTOS, A.H. ; BROCHADO, P. ; JUSTICA, B.
Date: 2003
Persistent ID: http://hdl.handle.net/10400.16/573
Origin: Repositório Científico do Centro Hospitalar do Porto
Description
Cytometry B Clin Cytom. 2003 Jan;51(1):41-4.
Guess what: Chronic 13q14.3+/CD5-/CD23+ lymphocytic leukemia in blood and t(11;14)(q13;q32)+/CD5+/CD23- mantle cell lymphoma in lymph nodes!
Lima M, Pinto L, Dos Anjos Teixeira M, Canelhas A, Mota A, Cabeda JM, Silva C, Queirós ML, Fonseca S, Santos AH, Brochado P, Justiça B.
Service of Clinical Hematology, Hospital Geral de Santo António, Porto, Portugal. mmc.lima@clix.pt
Abstract
We report a case of a patient with two B-cell lymphoproliferative disorders: CD5(-)/CD23(+) B-cell chronic lymphocytic leukemia and CD5(+)/CD23(-) mantle cell lymphoma. These disorders were diagnosed simultaneously based on flow cytometry, immunohistochemistry, fluorescence in situ hybridization, and polymerase chain reaction-based molecular studies. The B-cell lymphocytic leukemia clone predominated in the blood and bone marrow, whereas the mantle cell clone predominated in lymph nodes.
Copyright 2002 Wiley-Liss, Inc.
PMID: 12500296 [PubMed - indexed for MEDLINE]
