Slipped Capital Femoral Epiphysis. A Report of 4 Cases Occurring in One Family

• Author(s): Moreira, JF ; Neves, MC ; Lopes, G ; Gomes, AR
• Date: 1998
• Persistent ID: http://hdl.handle.net/10400.17/627
• Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
• Subject(s): Epífise Deslocada; Cabeça do Fémur; Obesidade; Fenótipo; Linhagem; Insulina
• Document Type: Article
• Language: English

Description

We describe slipped capital femoral epiphysis in 4 members of a black, obese family, who were all first-degree relatives. The aetiology of slipped capital femoral epiphysis is unknown, although it is thought to be multifactorial. Genetic predisposition and environmental factors have been associated with the condition. A familial incidence with at least two cases in the same family has been reported. In epidemiological studies, this incidence ranges from 3% to 35%. Our cases were investigated in an attempt to find a possible aetiological genetic factor. A genetic predisposition with an autosomal dominant pattern of transmission is suggested, although environmental variables must be considered as provocative factors.