Demographic and Clinical Characteristics of Human Immunodeficiency Virus-Infect...

• Author(s): Lopes, JA ; Abreu, F ; Almeida, E ; Carvalho, B ; Carmo, C ; Carvalho, D ; Barber, E ; Costa, F ; Silva, G ; Boquinhas, H ; Graça Silva, J ; Inchaustegui, L ; Dias, L ; Batista, M ; Neves, P ; Mendes, T
• Date: 2006
• Persistent ID: http://hdl.handle.net/10400.17/1109
• Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
• Subject(s): Portugal; HIV; Diálise; Estudos Retrospectivos; Epidemiologia
• Document Type: Article
• Language: English

Description

Background: Data on human immunodeficiency virus (HIV) infected patients receiving dialysis in Portugal is scarce. Methods: This nationwide epidemiological survey retrospectively evaluates HIV-infected patients on chronic dialysis in Portugal between 1997 and 2002. Results: Sixty-six patients were evaluated (mean age: 39.1±1.6 years, 47 men, 35 black African). Sixty-two patients started dialysis and 4 patients who were receiving dialysis had HIV seroconversion. Eighty-five percent of patients were treated in Lisbon. The annual incidence of HIV-infected patients on chronic dialysis was 0.5% in 1997 and 0.9% in 2002. Seventy-eight percent of patients were HIV-1 infected , 13% had hepatitis B and 31% hepatitis C. Sexual contact was the mode of transmission of HIV in 53% of cases. Four patients had biopsy-proved HIV-associated nephropathy. Ninety-five percent of patients were on chronic hemodialysis. Fifty percent of patients had acquired immunodeficiency syndrome. At follow-up, 12 patients died. HIV-infected CKD patient survival after starting dialysis was 80% at 3 years. Conclusion: The incidence of HIV-infected patients on chronic dialysis in Portugal has almost doubled. Widespread use of highly active antiretroviral therapy and the increasing number of black Africans from former overseas Portuguese colonies now living in Portugal are possible reasons for this large increase.