Synthesis and reactivity of 2-halo-2H-azirines towards nucleophiles

• Autor(es): Pinho e Melo, Teresa M. V. D. ; Lopes, Cláudia S. J. ; Gonsalves, António M. d'A. Rocha
• Data: 2000
• Identificador Persistente: http://hdl.handle.net/10316/5241
• Origem: Estudo Geral - Universidade de Coimbra
• Assunto(s): 2H-azirines; [alpha]-diimines; 3-oxazoline
• Tipo de Documento: Artigo
• Idioma: Inglês

Descrição

Nucleophilic substitution reactions of 2-halo-2H-azirine with potassium phthalimide and aniline allowed the preparation of new substituted 2H-azirines. The reactions of 2-bromo-3-phenyl-2H-azirine-2-carboxylate with methylamine led to the synthesis of [alpha]-diimines and from the reaction with water, a 3-oxazoline was obtained. http://www.sciencedirect.com/science/article/B6THS-4152YMR-K/1/e94005b66b66b6820ad27458f2562edd