Autor(es):
Schmitt, A. 
; Wapler, U. ; Couallier, V. ; Cunha, E.
Data: 2007
Identificador Persistente: http://hdl.handle.net/10316/3760
Origem: Estudo Geral - Universidade de Coimbra
Detalhes do Documento
Are bone losers distinguishable from bone formers in a skeletal series? Implica...
Descrição
Clinical studies indicate that genetic factors play a crucial role in primary osteoarthritis and osteoporosis. In addition, it has been suggested that these two diseases are inversely related. Within a population, one can find two sub-groups: the "bone formers" and the "bone losers". The changes to the joint surfaces used to assess adult age at death are related to the loss of bone substance and to bone formation (osteophytes). The modification of these indicators with age differs between bone formers and bone losers. Therefore, age-at-death assessment methods should make use of two standards, one for each sub-group. A preliminary study examining the possibility of distinguishing those who lose cortical bone from those who show signs of bony formation was conducted on a series of skeletons from Portugal, dating to the end of 19th century and the beginning of the 20th. Bone loss was evaluated using the cortical index (CI) of the second metacarpal on X-rays. The presence of osteophytes on dry bones was assessed macroscopically. http://www.sciencedirect.com/science/article/B7GW4-4MY114W-1/1/f17cf44e089dc09f083f559e325a8b1b
Clinical studies indicate that genetic factors play a crucial role in primary osteoarthritis and osteoporosis. In addition, it has been suggested that these two diseases are inversely related. Within a population, one can find two sub-groups: the "bone formers" and the "bone losers". The changes to the joint surfaces used to assess adult age at death are related to the loss of bone substance and to bone formation (osteophytes). The modification of these indicators with age differs between bone formers and bone losers. Therefore, age-at-death assessment methods should make use of two standards, one for each sub-group. A preliminary study examining the possibility of distinguishing those who lose cortical bone from those who show signs of bony formation was conducted on a series of skeletons from Portugal, dating to the end of 19th century and the beginning of the 20th. Bone loss was evaluated using the cortical index (CI) of the second metacarpal on X-rays. The presence of osteophytes on dry bones was assessed macroscopically. http://www.sciencedirect.com/science/article/B7GW4-4MY114W-1/1/f17cf44e089dc09f083f559e325a8b1b
Tipo de Documento
Artigo
Idioma Inglês
Idioma Inglês
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