Autor(es):
Rozenberg, M. 
; Shohama, G. ; Reva, I. ; Fausto, R.
Data: 2005
Identificador Persistente: http://hdl.handle.net/10316/17906
Origem: Estudo Geral - Universidade de Coimbra
Detalhes do Documento
Spontaneous self-association of adenine and uracil in polycrystals from low tem...
Descrição
FTIR spectra of solid samples of co-crystallized adenine and uracil were measured at 10 K in the range below 1000 cm−1. New bands ascribable to the N3H (uracil) and NH2 (adenine) out of plane vibrations, which disappear upon D-exchange, were revealed in comparison with the spectra of pure polycrystalline adenine and uracil obtained in the same conditions. The observed changes relate to the same groups that establish the H-bonds in base pairs of naturally occurring nucleic acids, despite the presence of an extra proton donor NH-group in both molecules. The well-established empirical correlation between the out of plane NH vibrational frequencies and H-bond energies was successfully applied for estimation of the latter in the mixed crystal.
FTIR spectra of solid samples of co-crystallized adenine and uracil were measured at 10 K in the range below 1000 cm−1. New bands ascribable to the N3H (uracil) and NH2 (adenine) out of plane vibrations, which disappear upon D-exchange, were revealed in comparison with the spectra of pure polycrystalline adenine and uracil obtained in the same conditions. The observed changes relate to the same groups that establish the H-bonds in base pairs of naturally occurring nucleic acids, despite the presence of an extra proton donor NH-group in both molecules. The well-established empirical correlation between the out of plane NH vibrational frequencies and H-bond energies was successfully applied for estimation of the latter in the mixed crystal.
Tipo de Documento
Artigo
Idioma Inglês
Idioma Inglês
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