An Efficient Methodology for the Synthesis of 3-Styryl Coumarins

• Author(s): Martins, Branco, P. S.
• Date: 2012
• Persistent ID: http://hdl.handle.net/10174/5150
• Origin: Repositório Científico da Universidade de Évora
• Subject(s): 3-vinyl coumarin; 3-styryl coumarin; Heck reaction; palladium; fluorescent dyes
• Document Type: Article
• Language: English

Description

Regioselective and highly efficient Heck arylation of 3-vinyl-6,7-dimethoxycoumarin has been developed to afford 3-styryl coumarins in good to very high yields. The increase in conjugation reflects on the absorbance of the synthesized compounds revealing all pronounced bathochromic shifts and hyperchromic effects.