New Methodology for the Synthesis of 3-Substituted Coumarins via Pd-Catalyzed S...

• Author(s): Martins, Sérgio ; Branco, Paula ; Torre, Maria ; Sierra, Miguel ; Pereira, António
• Date: 2010
• Persistent ID: http://hdl.handle.net/10174/3464
• Origin: Repositório Científico da Universidade de Évora
• Subject(s): coumarin; Heck reaction; 3-aryl coumarin; coupling reaction
• Document Type: Article
• Language: Portuguese

Description

A particularly useful, easy and concise synthesis of diversified 3-aryl coumarin was achieved using Heck coupling reactions between coumarin and aryliodides. The introduction of the aryl moiety occurred regioselective at the 3-position of the heteroaromatic ring.