New Methodology for the Synthesis of 3-Substituted Coumarins via Pd-Catalyzed S...

• Autor(es): Martins, Sérgio ; Branco, Paula ; Torre, Maria ; Sierra, Miguel ; Pereira, António
• Data: 2010
• Identificador Persistente: http://hdl.handle.net/10174/3464
• Origem: Repositório Científico da Universidade de Évora
• Assunto(s): coumarin; Heck reaction; 3-aryl coumarin; coupling reaction
• Tipo de Documento: Artigo
• Idioma: Português

Descrição

A particularly useful, easy and concise synthesis of diversified 3-aryl coumarin was achieved using Heck coupling reactions between coumarin and aryliodides. The introduction of the aryl moiety occurred regioselective at the 3-position of the heteroaromatic ring.