Pharmacological effects of strictosamide on Charles River mice

• Author(s): Morais, Júlio ; Candeias, Fátima ; Pereira, António ; Abreu, Pedro
• Date: 2002
• Persistent ID: http://hdl.handle.net/10174/3452
• Origin: Repositório Científico da Universidade de Évora
• Subject(s): Strictosamide; Pharmalogical effects
• Document Type: Lecture
• Language: English

Description

In previous publications we reported the isolation of indole alkaloids from the stem bark and roots of Sarcocephalus latifolius (Smith) Bruce (Nauclea latifolia Sm.)(Rubiaceae) collected in Guinea-Bissau, as well as antiplasmodial activity of its main constituent, strictosamide, wich accounts for 11% of the total ethanol extract. In this communication we present the pharmacological effects os strictosamide on Charles River mice.