Author(s):
Valle-Folgueral, JM 
; Mascarenhas, L ; Costa, JA ; Vieira, F ; Soares-Fernandes, J ; Beleza, P ; Alegria, C
Date: 2009
Origin: Repositório Comum
Subject(s): Neoplasias Cerebrais; Glioblastoma
Document details
Giant cell glioblastoma: review of the literature and illustrated case
Description
Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.
Giant cell glioblastoma is an infrequent variety of glioblastoma (5% of the cases). It has deserved a separate category in the World Health Organization classification of grade IV tumors. The clinical, imaging, histological and immunohistochemical characteristics, and the genetic alterations are reviewed. Treatment and prognosis are discussed and updated. The case of a patient that survived 19 months and died of spinal leptomeningeal metastases is illustrated.
Document Type
Article
Language English
Language English
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