Author(s):
Camões, Miguel 
; Oliveira, Andreia ; Pereira, Marta ; Severo, Milton ; Lopes, Carla
Date: 2010
Persistent ID: http://hdl.handle.net/10198/4659
Origin: Biblioteca Digital do IPB
Subject(s): Hypertension; Leisure-time physical activity; Fruits; Vegetables; Pulses; Potassium
Description
Background/Objectives: To evaluate longitudinally the role of physical activity (PA) (type and intensity) and diet (measured
using DASH score, nutrients and food intake) in hypertension incidence.
Subjects/Methods: As part of the EPIPorto study, 549 participants (X40 years), resident in Porto, Portugal, at risk of developing hypertension, were evaluated. Blood pressure (BP) measurements were obtained twice (1999–2003 and 2005–2008), with a median interval of 3.8 years. Hypertension was defined as systolic BP>=140mmHg and/or diastolic BP>=90mmHg, and/or if the subjects were under anti-hypertensive therapy. Validated questionnaires were used to assess usual PA and dietary intake during the previous year. Poisson regression was used to calculate the incident rate ratios (IRRs) and respective 95% confidence intervals (95% CIs). Results: In our population, the crude incidence rate (95% confidence interval (CI)) per 100 person-years of hypertension was
6.23 (5.26–7.20). After adjustment for several confounders, an inverse, though not significant, association was found across
increasing tertiles of leisure-time PA and IRR (95% CI): 1 (reference); 0.77 (0.51–1.16); and 0.74 (0.48–1.11). No significant associations between the DASH score and hypertension incidence were observed. However, potassium intake (mg/1000 kcal) was shown to be inversely associated with hypertension development (upper tertile: >1863.0 for women and >1657.2 for
men) vs first tertile (IRR=0.65 (0.44–0.96), P for trend=0.025). Additionally, in multivariate analysis, a significantly inverse association between the consumption of fruits/vegetables/pulses and hypertension incidence was found (upper vs first tertile:
IRR=0.61 (0.40–0.93), P for trend=0.024). Conclusions: In Portuguese adults, after adjustment for several confounders, the development of hypertension was inversely
associated with potassium and fruits/vegetables/pulses intake. A dose–response is inherent to these inverse associations.
