Separation of enantiomers by SMB chromatography: strategies of modeling and pro...

• Author(s): Pais, L.S. ; Rodrigues, A.E.
• Date: 1998
• Persistent ID: http://hdl.handle.net/10198/1599
• Origin: Biblioteca Digital do IPB
• Subject(s): Simulated moving bed; Modeling and simulation; Separation regions; Mass transfer resistance
• Document Type: Conference Object
• Language: English

Description

The paper deals with chiral separation by Simulated Moving Bed chromatography. A package for SMB simulation based on the analogy with the true moving bed is described. The package allows the prediction of regions for enantiomers separation. The influence of mass transfer resistance in the separation region is analyzed. A practical tool for choosing the better SMB operating conditions as a function of the feed flow rate is proposed.